190/2025

1.1.

Beschaffer

Offizielle Bezeichnung: Aalborg Universitet

2.1.

Verfahren

Titel: A60-MicroPLUS with microplate autosampler and KAIROS Microfluidic Sorting Module

Beschreibung: Our research is focused on developing EV-based biomarkers that are clinically applicable. For this, we have developed a method for measuring and characterizing nanosized particles, extracellular vesicles (EVs), directly in patient plasma samples (several published papers, one currently in review and several in preparation), requiring the highest level of sensitivity in a robust system is stable over time. To deliver EV-based research on the highest level, sensitivity, calibration, and standardization are of the essence when using high-resolution flow cytometry and a necessity when analyzing EVs. Moreover, since our research is clinically based, why we need the capacity to run multiple samples every day, by running samples on two instruments simultaneously. We thus, need a high-resolution flow cytometer that deliver data, directly comparable with our current instrument. In addition, we are currently developing methods for isolation of tissue-specific EV-populations to expand both insight in their involvement in tissue-specific diseases and thus, advance the future use of EV-based functional biomarker for detecting tissue-specific complications. Here an EV-sorter is a game changer that will significantly improve our research outcome by providing purification (sorting) of highly specific and pure EV-populations. We thus need a high-resolution flow cytometer and EV-sorter that combines the level of resolution (in particular on light scatter), stability (doi: 10.3390/biomedicines9020124), ability to run 96-well plates (autosampler function), delivery of data that is directly comparable to current (to run clinical studies with a size (sample numbers) to deliver the necessary statistical power, needed for advancing EV-biomarker development) and sorter function that our research projects requires. The Apogee instrument offers resolution using a third light scatter detector (medium angle range, MALS) offer the best resolution of populations (particle size resolution) by light scatter. Moreover, the Apogee instrument has highly advanced ‘IOTA’ model data acquisition electronics with tunable digital pulse filtering, allowing the flow velocity to be slowed down to increase sensitivity (both light scatter and fluorescence sensitivity) as well as 96-well plate autosampler analysis option. Finally, Apogee offers a particle size meta parameter (light scatter calibration), which is a unique method patented by ApogeeFlow offering a relatively easy calibration to SI units. The Kairos sorter included in the Apogee system is the only sorter of its type on the market (patent applies) with an electric field driven microfluidic sorter, offering fast sorting of specific EV-populations.

Kennung des Verfahrens: fcc91ee0-80f6-4b64-b1af-c388d7770b13

Interne Kennung: f578b2c5-25f9-49dd-bbf4-416d783d07b8

Verfahrensart: Verhandlungsverfahren ohne Aufruf zum Wettbewerb

2.1.1.

Zweck

Art des Auftrags: Lieferleistungen

Haupteinstufung (cpv): 38000000 Laborgeräte, optische Geräte und Präzisionsgeräte (außer Gläser)

2.1.2.

Erfüllungsort

Postanschrift: Selma Lagerløfs Vej 249

Stadt: Gistrup

Postleitzahl: 9260

Land, Gliederung (NUTS): Nordjylland (DK050)

Land: Dänemark

2.1.4.

Allgemeine Informationen

Rechtsgrundlage:

Richtlinie 2014/24/EU

5.1.

Los: LOT-0000

Titel: A60-MicroPLUS with microplate autosampler and KAIROS Microfluidic Sorting Module

Beschreibung: Our research is focused on developing EV-based biomarkers that are clinically applicable. For this, we have developed a method for measuring and characterizing nanosized particles, extracellular vesicles (EVs), directly in patient plasma samples (several published papers, one currently in review and several in preparation), requiring the highest level of sensitivity in a robust system is stable over time. To deliver EV-based research on the highest level, sensitivity, calibration, and standardization are of the essence when using high-resolution flow cytometry and a necessity when analyzing EVs. Moreover, since our research is clinically based, why we need the capacity to run multiple samples every day, by running samples on two instruments simultaneously. We thus, need a high-resolution flow cytometer that deliver data, directly comparable with our current instrument. In addition, we are currently developing methods for isolation of tissue-specific EV-populations to expand both insight in their involvement in tissue-specific diseases and thus, advance the future use of EV-based functional biomarker for detecting tissue-specific complications. Here an EV-sorter is a game changer that will significantly improve our research outcome by providing purification (sorting) of highly specific and pure EV-populations. We thus need a high-resolution flow cytometer and EV-sorter that combines the level of resolution (in particular on light scatter), stability (doi: 10.3390/biomedicines9020124), ability to run 96-well plates (autosampler function), delivery of data that is directly comparable to current (to run clinical studies with a size (sample numbers) to deliver the necessary statistical power, needed for advancing EV-biomarker development) and sorter function that our research projects requires. The Apogee instrument offers resolution using a third light scatter detector (medium angle range, MALS) offer the best resolution of populations (particle size resolution) by light scatter. Moreover, the Apogee instrument has highly advanced ‘IOTA’ model data acquisition electronics with tunable digital pulse filtering, allowing the flow velocity to be slowed down to increase sensitivity (both light scatter and fluorescence sensitivity) as well as 96-well plate autosampler analysis option. Finally, Apogee offers a particle size meta parameter (light scatter calibration), which is a unique method patented by ApogeeFlow offering a relatively easy calibration to SI units. The Kairos sorter included in the Apogee system is the only sorter of its type on the market (patent applies) with an electric field driven microfluidic sorter, offering fast sorting of specific EV-populations.

Interne Kennung: be4f9a00-6d24-43d9-b943-919b7e34096f

5.1.1.

Zweck

Art des Auftrags: Lieferleistungen

Haupteinstufung (cpv): 38000000 Laborgeräte, optische Geräte und Präzisionsgeräte (außer Gläser)

5.1.2.

Erfüllungsort

Postanschrift: Selma Lagerløfs Vej 249

Stadt: Gistrup

Postleitzahl: 9260

Land, Gliederung (NUTS): Nordjylland (DK050)

Land: Dänemark

5.1.6.

Allgemeine Informationen

Die Beschaffung fällt unter das Übereinkommen über das öffentliche Beschaffungswesen: ja

5.1.15.

Techniken

Rahmenvereinbarung:

Keine Rahmenvereinbarung

Informationen über das dynamische Beschaffungssystem:

Kein dynamisches Beschaffungssystem

5.1.16.

Weitere Informationen, Schlichtung und Nachprüfung

Überprüfungsstelle: Klagenævnet for Udbud

Organisation, die zusätzliche Informationen über das Vergabeverfahren bereitstellt: Aalborg Universitet

Organisation, die weitere Informationen für die Nachprüfungsverfahren bereitstellt: Konkurrence- og Forbrugerstyrelsen

Organisation, aus deren Mitteln der Auftrag bezahlt wird: Aalborg Universitet

Direktvergabe:

Begründung der Direktvergabe: Der Auftrag kann nur von einem bestimmten Wirtschaftsteilnehmer ausgeführt werden, da aus technischen Gründen kein Wettbewerb vorhanden ist

Sonstige Begründung: Our research is focused on developing EV-based biomarkers that are clinically applicable. For this, we have developed a method for measuring and characterizing nanosized particles, extracellular vesicles (EVs), directly in patient plasma samples (several published papers, one currently in review and several in preparation), requiring the highest level of sensitivity in a robust system is stable over time. To deliver EV-based research on the highest level, sensitivity, calibration, and standardization are of the essence when using high-resolution flow cytometry and a necessity when analyzing EVs. Moreover, since our research is clinically based, why we need the capacity to run multiple samples every day, by running samples on two instruments simultaneously. We thus, need a high-resolution flow cytometer that deliver data, directly comparable with our current instrument. In addition, we are currently developing methods for isolation of tissue-specific EV-populations to expand both insight in their involvement in tissue-specific diseases and thus, advance the future use of EV-based functional biomarker for detecting tissue-specific complications. Here an EV-sorter is a game changer that will significantly improve our research outcome by providing purification (sorting) of highly specific and pure EV-populations. We thus need a high-resolution flow cytometer and EV-sorter that combines the level of resolution (in particular on light scatter), stability (doi: 10.3390/biomedicines9020124), ability to run 96-well plates (autosampler function), delivery of data that is directly comparable to current (to run clinical studies with a size (sample numbers) to deliver the necessary statistical power, needed for advancing EV-biomarker development) and sorter function that our research projects requires. The Apogee instrument offers resolution using a third light scatter detector (medium angle range, MALS) offer the best resolution of populations (particle size resolution) by light scatter. Moreover, the Apogee instrument has highly advanced ‘IOTA’ model data acquisition electronics with tunable digital pulse filtering, allowing the flow velocity to be slowed down to increase sensitivity (both light scatter and fluorescence sensitivity) as well as 96-well plate autosampler analysis option. Finally, Apogee offers a particle size meta parameter (light scatter calibration), which is a unique method patented by ApogeeFlow offering a relatively easy calibration to SI units. The Kairos sorter included in the Apogee system is the only sorter of its type on the market (patent applies) with an electric field driven microfluidic sorter, offering fast sorting of specific EV-populations.

6.1.

Ergebnis, Los-– Kennung: LOT-0000

6.1.2.

Informationen über die Gewinner

Wettbewerbsgewinner:

Offizielle Bezeichnung: Apogee Flow Systems Ltd

Angebot:

Kennung des Angebots: Apogee Flow Systems Ltd

Kennung des Loses oder der Gruppe von Losen: LOT-0000

Wert des Angebots: 2 058 175,11 DKK

Das Angebot wurde in die Rangfolge eingeordnet: nein

Informationen zum Auftrag:

Kennung des Auftrags: A60-MicroPLUS with microplate autosampler and KAIROS Microfluidic Sorting Module

8.1.

ORG-0001

Offizielle Bezeichnung: Aalborg Universitet

Registrierungsnummer: 29102384

Postanschrift: Fredrik Bajers Vej 7K

Stadt: Aalborg Øst

Postleitzahl: 9220

Land, Gliederung (NUTS): Nordjylland (DK050)

Land: Dänemark

Kontaktperson: Alexander Herskind Rasmussen

E-Mail: ahra@adm.aau.dk

Telefon: 22505186

Rollen dieser Organisation:

Beschaffer

Organisation, die zusätzliche Informationen über das Vergabeverfahren bereitstellt

Organisation, aus deren Mitteln der Auftrag bezahlt wird

8.1.

ORG-0002

Offizielle Bezeichnung: Klagenævnet for Udbud

Registrierungsnummer: 37795526

Postanschrift: Toldboden 2

Stadt: Viborg

Postleitzahl: 8800

Land, Gliederung (NUTS): Vestjylland (DK041)

Land: Dänemark

Kontaktperson: Klagenævnet for Udbud

E-Mail: klfu@naevneneshus.dk

Telefon: +45 72405600

Endpunkt für den Informationsaustausch (URL): https://naevneneshus.dk/start-din-klage/klagenaevnet-for-udbud/

Rollen dieser Organisation:

Überprüfungsstelle

8.1.

ORG-0003

Offizielle Bezeichnung: Konkurrence- og Forbrugerstyrelsen

Registrierungsnummer: 10294819

Postanschrift: Carl Jacobsens Vej 35

Stadt: Valby

Postleitzahl: 2500

Land, Gliederung (NUTS): Byen København (DK011)

Land: Dänemark

Kontaktperson: Konkurrence- og Forbrugerstyrelsen

E-Mail: kfst@kfst.dk

Telefon: +45 41715000

Endpunkt für den Informationsaustausch (URL): https://www.kfst.dk

Rollen dieser Organisation:

Organisation, die weitere Informationen für die Nachprüfungsverfahren bereitstellt

8.1.

ORG-0004

Offizielle Bezeichnung: Apogee Flow Systems Ltd

Stadt: Northwood

Postleitzahl: HA6 3HU

Land: Vereinigtes Königreich

Rollen dieser Organisation:

Bieter

Gewinner dieser Lose: LOT-0000

8.1.

ORG-0005

Offizielle Bezeichnung: Mercell Holding ASA

Registrierungsnummer: 980921565

Postanschrift: Askekroken 11

Stadt: Oslo

Postleitzahl: 0277

Land, Gliederung (NUTS): Oslo (NO081)

Land: Norwegen

Kontaktperson: eSender

E-Mail: publication@mercell.com

Telefon: +47 21018800

Fax: +47 21018801

Internetadresse: http://mercell.com/

Rollen dieser Organisation:

TED eSender

Kennung/Fassung der Bekanntmachung: b5c25f82-f7a9-47a0-b444-5ccc289b7263 - 01

Formulartyp: Vorankündigung – Direktvergabe

Art der Bekanntmachung: Freiwillige Ex-ante-Transparenzbekanntmachung

Unterart der Bekanntmachung: 25

Datum der Übermittlung der Bekanntmachung: 02/10/2025 07:39:35 (UTC+00:00) Westeuropäische Zeit, GMT

Bekanntmachung — eSender-Übermittlungsdatum: 02/10/2025 07:40:25 (UTC+00:00) Westeuropäische Zeit, GMT

Sprachen, in denen diese Bekanntmachung offiziell verfügbar ist: Englisch

Veröffentlichungsnummer der Bekanntmachung: 647740-2025

ABl. S – Nummer der Ausgabe: 190/2025

Datum der Veröffentlichung: 03/10/2025