Services - 248738-2021

18/05/2021    S95

Italy-Parma: Development of in Silico Methodologies to Predict the Toxicity of Proteins in Food and Feed Risk Assessment

2021/S 095-248738

Prior information notice

This notice is for prior information only

Services

Legal Basis:
Regulation (EU, Euratom) No 2018/1046

Section I: Contracting authority

I.1)Name and addresses
Official name: European Food Safety Authority (EFSA)
Postal address: Via Carlo Magno 1A
Town: Parma
NUTS code: ITH52 Parma
Postal code: 43126
Country: Italy
E-mail: EFSAProcurement@efsa.europa.eu
Internet address(es):
Main address: http://www.efsa.europa.eu/en/procurement/tenders.htm
Address of the buyer profile: http://www.efsa.europa.eu/en/procurement/tenders.htm
I.3)Communication
Additional information can be obtained from the abovementioned address
I.4)Type of the contracting authority
European institution/agency or international organisation
I.5)Main activity
General public services

Section II: Object

II.1)Scope of the procurement
II.1.1)Title:

Development of in Silico Methodologies to Predict the Toxicity of Proteins in Food and Feed Risk Assessment

II.1.2)Main CPV code
73000000 Research and development services and related consultancy services
II.1.3)Type of contract
Services
II.1.4)Short description:

The target of the work is to explore in silico methodologies to predict protein toxicity, and to identify candidate approaches to be implemented as tools supporting food/feed risk assessment. The implementation of the identified methodology is not part of this call. In silico methodologies to consider can span from ‘traditional’ sequence similarity analysis to artificial intelligence (e.g. machine learning, deep learning). Approaches should search for structural and functional homology of the protein of interest to toxic proteins; and/or for the presence in the protein itself of ‘toxic molecular signatures’, i.e. structural/functional properties relevant in the molecular initiating events leading to toxicity. The identified methodologies should allow to predict the potential toxicity of a protein of interest, and to infer the elicited type of toxicity, the toxicity mechanisms and the potential target tissue/s. A proposal for defining threshold criteria should be identified.

II.1.5)Estimated total value
Value excluding VAT: 200 000.00 EUR
II.1.6)Information about lots
This contract is divided into lots: no
II.2)Description
II.2.3)Place of performance
NUTS code: ITH52 Parma
II.2.4)Description of the procurement:

Precise description of the services will be published in the tender specifications of the open call for tenders. All the information published in this prior information notice is to be considered an estimate subject to possible revision.

II.2.14)Additional information

All the information published in this prior information notice is to be considered an estimate subject to possible revision.

II.3)Estimated date of publication of contract notice:
30/06/2021

Section IV: Procedure

IV.1)Description
IV.1.8)Information about the Government Procurement Agreement (GPA)
The procurement is covered by the Government Procurement Agreement: no

Section VI: Complementary information

VI.3)Additional information:
VI.5)Date of dispatch of this notice:
11/05/2021