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Services - 159288-2022

28/03/2022    S61

Italy-Parma: Implementation of a Multi-OMICs and Inter-species Workflow to Derive Human Reference Points and Health-based Guidance Values (HBGVs) from Quantitative in Vitro Data

2022/S 061-159288

Contract notice

Services

Legal Basis:
Regulation (EU, Euratom) No 2018/1046

Section I: Contracting authority

I.1)Name and addresses
Official name: European Food Safety Authority (EFSA)
Postal address: Via Carlo Magno 1A
Town: Parma
NUTS code: ITH52 Parma
Postal code: 43126
Country: Italy
E-mail: EFSAProcurement@efsa.europa.eu
Internet address(es):
Main address: https://etendering.ted.europa.eu/general/page.html?name=home&locale=en
Address of the buyer profile: http://www.efsa.europa.eu/en/procurement/tenders.htm
I.3)Communication
The procurement documents are available for unrestricted and full direct access, free of charge, at: https://etendering.ted.europa.eu/cft/cft-display.html?cftId=10539
Additional information can be obtained from the abovementioned address
Tenders or requests to participate must be submitted electronically via: https://etendering.ted.europa.eu/cft/cft-display.html?cftId=10539
I.4)Type of the contracting authority
European institution/agency or international organisation
I.5)Main activity
General public services

Section II: Object

II.1)Scope of the procurement
II.1.1)Title:

Implementation of a Multi-OMICs and Inter-species Workflow to Derive Human Reference Points and Health-based Guidance Values (HBGVs) from Quantitative in Vitro Data

Reference number: OC/EFSA/IDATA/2022/01
II.1.2)Main CPV code
73000000 Research and development services and related consultancy services
II.1.3)Type of contract
Services
II.1.4)Short description:

The overarching goal of the project is to define, validate and apply a standardised workflow (experimental and computational) for deriving reliable human reference points and HBGVs using cutting edge in-vitro approaches, namely organ-on-a-chip (OoC) platforms and multiple OMICs endpoints (transcriptomics, metabolomics, epigenomics).

II.1.5)Estimated total value
Value excluding VAT: 3 250 000.00 EUR
II.1.6)Information about lots
This contract is divided into lots: yes
Tenders may be submitted for all lots
II.2)Description
II.2.1)Title:

Implementation of a Multi-OMICs and Inter-species Workflow (Objective 1)

Lot No: 1
II.2.2)Additional CPV code(s)
73000000 Research and development services and related consultancy services
II.2.3)Place of performance
NUTS code: ITH52 Parma
II.2.4)Description of the procurement:

• Objective 1: Implementation of a multi-OMICs and inter-species workflow. In phase one, a set of data-rich substances will be selected (6 to 12 compounds) and used for an extensive toxicological screening based on OoC and multi-OMICs profiling (transcriptomics, epigenomics, metabolomics). Selected substances will include legacy hazards in food/feed and compounds/nutrients with positive health claims (e.g. resveratrol, to be used to verify applicability of OMICs in assessing beneficial dietary effects). The experimental design will be largely based on the procedures established in EU ToxRisk.

II.2.5)Award criteria
Price is not the only award criterion and all criteria are stated only in the procurement documents
II.2.6)Estimated value
Value excluding VAT: 3 000 000.00 EUR
II.2.7)Duration of the contract, framework agreement or dynamic purchasing system
Duration in months: 36
This contract is subject to renewal: no
II.2.10)Information about variants
Variants will be accepted: no
II.2.11)Information about options
Options: no
II.2.13)Information about European Union funds
The procurement is related to a project and/or programme financed by European Union funds: no
II.2.14)Additional information
II.2)Description
II.2.1)Title:

Lot 2 – Inference of Chemical Grouping from Processed OMICS Data in CTD (Objective 2)

Lot No: 2
II.2.2)Additional CPV code(s)
73000000 Research and development services and related consultancy services
II.2.3)Place of performance
NUTS code: ITH52 Parma
II.2.4)Description of the procurement:

• Objective 2: Inference of chemical grouping from processed OMICS data in the comparative toxicogenomics database (CTD).

II.2.5)Award criteria
Price is not the only award criterion and all criteria are stated only in the procurement documents
II.2.6)Estimated value
Value excluding VAT: 250 000.00 EUR
II.2.7)Duration of the contract, framework agreement or dynamic purchasing system
Duration in months: 12
This contract is subject to renewal: no
II.2.10)Information about variants
Variants will be accepted: no
II.2.11)Information about options
Options: no
II.2.13)Information about European Union funds
The procurement is related to a project and/or programme financed by European Union funds: no
II.2.14)Additional information

Section III: Legal, economic, financial and technical information

III.1)Conditions for participation
III.1.1)Suitability to pursue the professional activity, including requirements relating to enrolment on professional or trade registers
List and brief description of conditions:

As stated in the procurement documents.

III.1.2)Economic and financial standing
Selection criteria as stated in the procurement documents
III.1.3)Technical and professional ability
Selection criteria as stated in the procurement documents

Section IV: Procedure

IV.1)Description
IV.1.1)Type of procedure
Open procedure
IV.1.3)Information about a framework agreement or a dynamic purchasing system
IV.1.8)Information about the Government Procurement Agreement (GPA)
The procurement is covered by the Government Procurement Agreement: no
IV.2)Administrative information
IV.2.1)Previous publication concerning this procedure
Notice number in the OJ S: 2022/S 030-073020
IV.2.2)Time limit for receipt of tenders or requests to participate
Date: 15/06/2022
Local time: 14:30
IV.2.3)Estimated date of dispatch of invitations to tender or to participate to selected candidates
IV.2.4)Languages in which tenders or requests to participate may be submitted:
English, Bulgarian, Danish, German, Greek, Estonian, Finnish, French, Irish, Croatian, Hungarian, Italian, Latvian, Lithuanian, Maltese, Dutch, Polish, Portuguese, Romanian, Slovak, Slovenian, Spanish, Swedish, Czech
IV.2.6)Minimum time frame during which the tenderer must maintain the tender
Duration in months: 9 (from the date stated for receipt of tender)
IV.2.7)Conditions for opening of tenders
Date: 16/06/2022
Local time: 14:30
Place:

Virtual opening.

Section VI: Complementary information

VI.1)Information about recurrence
This is a recurrent procurement: no
VI.3)Additional information:

‘In case of unavailability or disruptions in the functioning of the electronic means of communication provided in Section I.3) in the last five calendar days before the time limit for receipt indicated in Section IV.2.2), the contracting authority reserves the right to extend this time limit and publish the extension at the internet address provided in Section I.3), without a preceding publication of a corrigendum to this notice. Economic operators interested in this procurement are invited to subscribe to the call for tenders at the address in Section I.3) in order to get notified when new information or documents are published.’

VI.4)Procedures for review
VI.4.1)Review body
Official name: General Court of the European Union
Postal address: rue du Fort Niedergrünewald
Town: Luxembourg
Postal code: L-2925
Country: Luxembourg
E-mail: generalcourt.registry@curia.europa.eu
Telephone: +352 4303-1
Fax: +352 4303-2100
Internet address: http://curia.europa.eu
VI.5)Date of dispatch of this notice:
21/03/2022